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About ZanthoSyn®

ZanthoSyn® is a dietary supplement containing astaxanthin, a clinically studied ingredient with safe anti-inflammatory activity that supports joint health, cardiovascular health, metabolic health, and liver health.* Astaxanthin is a naturally occurring compound found in algae, krill, salmon, shrimp, and lobster, and can be sourced naturally by extraction from algae, krill, or salmon or manufactured by synthesis in high purity.

Cardax ZanthoSyn® features synthetic astaxanthin in high purity and with superior absorption. After oral ingestion, ZanthoSyn® is transported throughout the body, where it safely supports healthy anti-inflammatory activity at the cellular and mitochondrial level without inhibiting normal function.*

ZanthoSyn® is available for purchase online at and can be found at GNC stores across the United States.

Health Applications

Cardiovascular Health

Astaxanthin localizes in the heart and has been shown to significantly reduce LDL-cholesterol, triglycerides, and blood pressure in human clinical trials, which are critical to maintaining cardiovascular health. Animal studies with astaxanthin have also demonstrated positive effects in models of heart health.*

Metabolic Health

In human clinical trials, astaxanthin has been shown to benefit metabolic health by increasing the metabolic regulator adiponectin. In animal studies, astaxanthin also decreased fasting blood glucose levels by impacting insulin signaling and sensitivity, which is critical to maintaining metabolic health.*

Liver Health

Astaxanthin is stored in the liver and repackaged for distribution throughout the body. Human clinical trials with astaxanthin have demonstrated benefits in liver health as measured by fat accumulation in the liver. Animal studies also support astaxanthin and liver health.*

Joint Health

In human clinical trials, astaxanthin has been shown to significantly reduce markers of inflammation critical to healthy joint function, including TNF-alpha and CRP. Animal studies with astaxanthin also demonstrated reduction in inflammatory mediators and maintenance of joint structure.*


In human studies, activation of the FOXO3 gene has been linked to decreased inflammation and aging. In animal studies, astaxanthin statistically significantly decreased activated the FOXO3 gene and extended lifespan.*

Physician Endorsed

Healthcare professionals recommend ZanthoSyn® because of its manufacturing rigor and excellent absorption. Its synthetic manufacturing provides astaxanthin in the high purity and consistency necessary for dose control and establishment of astaxanthin blood levels, which are critical for managing inflammation and maintaining health.*

Established Safety

ZanthoSyn® contains astaxanthin, which has been extensively used in animal and human health and has been present in our food chain for thousands of years. The safety of astaxanthin has been well established through the FDA’s process for determining the acceptable daily intake of dietary supplements. The form of astaxanthin utilized in ZanthoSyn® is also Generally Recognized as Safe (GRAS) according to FDA regulations.

Environmentally Friendly and Sustainable

Research has demonstrated that synthetic production of astaxanthin emits fewer greenhouse gases and consumes less energy, raw material, and land than natural astaxanthin production. With the growing need for a safe anti-inflammatory to support general health, an environmentally friendly and sustainable solution is critical.

ZanthoSyn®: High Purity Astaxanthin with Superior Absorption

ZanthoSyn® contains pure astaxanthin prepared by natural product total synthesis. In contrast, the astaxanthin extracted from algae and krill oil is obtained in a complex mixture, which may include many unknown marine byproducts. The precision of synthetic manufacturing also provides healthcare professionals and health-conscious consumers with confidence in the quality and consistency of dosing from every capsule. ZanthoSyn® is manufactured in accordance with cGMP regulations.


In a human study comparing ZanthoSyn® to a leading natural astaxanthin product, the astaxanthin blood levels following administration of ZanthoSyn® were nearly 3 times higher than the other astaxanthin product at the same dose of 24 mg. This means that two 12 mg capsules of ZanthoSyn® deliver nearly the same amount of astaxanthin to the blood stream as six 12 mg capsules of natural astaxanthin. And research studies suggest that higher blood levels of astaxanthin may provide greater health benefits.