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Protective Effect of Astaxanthin on Liver Fibrosis through Modulation of TGF-β1 Expression and Autophagy. Shen et al.

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By Timothy J. King, Ph.D., Vice President, Research The role of oxidative stress and inflammation in liver injury and liver dysfunction as well as the potential for antioxidants to ameliorate liver disease has been established in both animal models and human trials [Sanchez-Valle et al. 2012; Pacana and Sanyal 2012]. Studies utilizing rodent models of liver disease have also demonstrated the efficacy of astaxanthin (ASTX) in ameliorating liver injury [Kang et al. 2001; Curek et…

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